Key result
In subjects with generalised anxiety disorder, cardiac vagal tone did not differ from controls, but the non-invasive RSA method underestimated vagal tone due to higher respiratory rates.
Why the study?
Does the non-invasive measurement of respiratory sinus arrhythmia accurately estimate cardiac vagal tone in subjects with generalised anxiety disorder compared to an invasive pharmacological method?
Case-Control
Does the non-invasive measurement of respiratory sinus arrhythmia accurately estimate cardiac vagal tone in subjects with generalised anxiety disorder compared to an invasive pharmacological method?
The non-invasive RSA method underestimates cardiac vagal tone in generalized anxiety disorder due to higher respiratory rates, despite actual vagal tone being similar to controls.
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Non-invasive RSA underestimates vagal tone in GAD; leaves open validation of respiratory-adjusted methods against invasive standards.
Kollai et al. (1992) conducted a case-control in Generalised anxiety disorder. Invasive pharmacological method and non-invasive RSA method vs. Control subjects was evaluated on Cardiac vagal tone and amplitude of respiratory sinus arrhythmia (RSA). In subjects with generalised anxiety disorder, cardiac vagal tone did not differ from controls, but the non-invasive RSA method underestimated vagal tone due to higher respiratory rates.
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