Why the study?
AF is associated with arterial thromboembolism, but venous thromboembolism in AF is less well studied.
Does atrial fibrillation increase the risk of venous thromboembolism compared to matched population controls?
Population
463 244 AF cases and 887 336 matched population controls in Sweden
Comparison
AF cases vs matched controls without AF
Design
Nationwide registry study
Authors
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AF diagnosis associates with high early VTE rates; hypothesis-generating for anticoagulation timing trials but should not change practice.
Does atrial fibrillation increase the risk of venous thromboembolism compared to matched population controls?
Atrial fibrillation is strongly associated with an increased risk of venous thromboembolism during the first months after diagnosis, suggesting early anticoagulant therapy may be beneficial.
Hornestam et al. (2021) studied this question.
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