Key result
Prospective screening reveals an ~8-fold increase in EV-D68 detection in autumn 2014 versus 2013.
Population
Outpatients with influenza-like illness and inpatient/outpatient EV-D68 cases in three Canadian provinces.
Comparison
Prospective screening for enterovirus-D68 from… vs Specimens collected from October 1, 2013 to July…
Design
Cross-sectional
Authors
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EV-D68 surveillance data warrant clinical vigilance for pediatric ILI in autumn; leaves open need for prospective studies to quantify hospitalization risk and guide responses.
Observational (n=1,894)
Yes
Absolute Event Rate: 2.4% vs 0.3%
p-value: p=0.01
Surveillance in Canada demonstrated an epidemic circulation of EV-D68 in autumn 2014 with higher hospitalization incidence in pediatric populations.
Skowronski et al. (2015) conducted an observational in Enterovirus-D68 / Influenza-like illness (n=1,894). Prospective screening for EV-D68 (August-December 2014) vs. Historical specimens (October 2013-July 2014) was evaluated on EV-D68 detection rate (p=0.01). Prospective screening for EV-D68 in Canadian outpatients with influenza-like illness revealed an 8-fold increase in detection rates in autumn 2014 (2.4%) compared to autumn 2013 (0.3%, p=0.01).
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