Key result
Ross procedure achieves ~92% 10-year freedom from autograft reoperation, though age and sinus size predict dilatation.
Why the study?
Pulmonary autograft dilation is the primary cause of reoperation after the Ross procedure, prompting evaluation of its prevalence and risk factors.
Cohort (n=158)
No
Effect estimate: OR 0.942 (age); OR 1.18 (initial size of sinuses of Valsalva) (95% CI 0.901-0.984; 1.027-1.215)
p-value: p=0.008; 0.01
Following the classical Ross procedure in adults, younger age and larger initial diameter of the sinuses of Valsalva are significant predictors of long-term pulmonary autograft dilatation.
Introduction. Aortic valve replacement with pulmonary autograft (Ross procedure) demonstrated excellent immediate and long-term results. Dilation of the pulmonary autograft in the long-term period is the main reason for repeated surgery. Aim: to study the prevalence of pulmonary autograft dilatation and its risk factors. Materials and methods. From April 2009 to December 2022, 158 patients underwent classical Ross surgery. Inclusion criteria: patients aged 18 and older, patients who underwent classical surgery. Exclusion criteria: patients under 18, modifi ed methods of Ross procedure. Follow-up period: 104 (49–124) months. Results and discussion. The median age of patients was 33 (25–43) years. Hospital mortality accounted for 0.6 %. Perioperative myocardial injury was 3.8 %, conduction disorder requiring permanent pacemaker implantation accounted for 1.9 %, the incidence of strokes and acute kidney injury requiring hemodialysis was 0.6 %. Ten-year freedom from autograft reoperation was 88.4. Ten-year freedom from reoperation for aortic aneurysm accounted for 92 %. Predictors of autograft dilatation in the long-term period were: age (OR: 0.942; 95% CI: 0.901–0.984, p = 0.008) and the initial size of sinuses of Valsalva (OR: 1.18; 95% CI: 1.027–1.215, p = 0.01). Conclusion. Ten-year freedom from autograft reoperation due to aortic dilatation and freedom from aortic dilatation ≥ 45 mm was 92 % and 37.2 %, respectively. The main predictors of autograft dilatation in the postoperative period are the age and the initial diameter of the sinuses of Valsalva.
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Чернов et al. (2023) conducted a cohort in Aortic valve replacement (Ross procedure) (n=158). Classical Ross procedure was evaluated on Predictors of autograft dilatation (OR 0.942 (age); OR 1.18 (initial size of sinuses of Valsalva), 95% CI 0.901-0.984; 1.027-1.215, p=0.008; 0.01). Following the classical Ross procedure, 10-year freedom from autograft reoperation due to aortic dilatation was 92%, with age (OR 0.942) and initial sinus of Valsalva size (OR 1.18) as predictors.
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