Why the study?
Does left atrial volume index (LAVI) predict AF recurrence following PVI by means of 2nd-generation cryoballoon in patients with persistent vs paroxysmal AF?
Does left atrial volume index (LAVI) predict AF recurrence following PVI by means of 2nd-generation cryoballoon in patients with persistent vs paroxysmal AF?
Second-generation cryoballoon ablation shows equivalent mid-term efficacy for persistent and paroxysmal atrial fibrillation, with left atrial volume index acting as a predictor of recurrence.
LAVI may aid recurrence risk stratification after cryoballoon PVI; supports equivalent PeAF/PAF efficacy but requires prospective validation.
BACKGROUND: Pulmonary vein isolation (PVI) by means of cryoballoon is increasingly being used for the treatment of atrial fibrillation (AF). This study assessed whether the left atrial volume index (LAVI) predicts AF recurrence following PVI by means of 2nd-generation cryoballoon (Cryoballoon Advance; CB-A) when comparing persistent AF (PeAF) and paroxysmal AF (PAF). METHODS AND RESULTS: (hazard ratio 5.771, 95% confidence interval 2.434-13.682, P<0.001), and the mid-term success rate was comparable with PAF patients. CONCLUSIONS: , the mid-term efficacy among PeAF patients was equivalent to that for PAF patients.
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Takarada et al. (2018) studied this question.
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