Key result
A normal left atrial volume index strongly predicted procedural success after cryoballoon ablation for persistent atrial fibrillation, achieving a 71.0% arrhythmia-free survival.
Why the study?
Pulmonary vein isolation using cryoballoon ablation is increasingly performed as a first-line treatment for persistent atrial fibrillation, but follow-up data and predictors of procedural success are lacking.
Does left atrial volume index predict arrhythmia-free survival in patients with persistent atrial fibrillation undergoing cryoballoon ablation?
Cohort (n=148)
Does left atrial volume index predict arrhythmia-free survival in patients with persistent atrial fibrillation undergoing cryoballoon ablation?
Left atrial volume index is a strong predictor of arrhythmia-free survival in patients with persistent atrial fibrillation undergoing cryoballoon ablation.
LAVI may refine pre-ablation risk stratification in persistent AF; leaves open whether prospective use improves outcomes.
BACKGROUND: Pulmonary vein isolation (PVI) using cryoballoon ablation (PVI-C) is increasingly performed as a first-line strategy for the treatment of patients with persistent atrial fibrillation (PersAF); however, follow-up data and predictors of procedural success are lacking. OBJECTIVE: To study the efficacy of PVI-C in patients with PersAF, focusing on predictors of procedural success. METHODS: By retrospective review, 148 consecutive patients with PersAF who underwent PVI-C were analyzed. The impact of several variables on outcome was evaluated in univariate and multivariate analyses and Cox proportional hazards regression models. RESULTS: After a mean follow-up of 19.2±10.9 months, 75 (50.7%) patients remained arrhythmia-free without the need for antiarrhythmic drug therapy. Patients with a normal left atrial volume index (LAVI) achieved a 71.0% arrhythmia-free survival. LAVI was the most powerful predictor of procedural success. CONCLUSIONS: Arrhythmia-free survival after PVI-C in select patients with PersAF are promising. Moreover, LAVI is a valuable measurement to help guide ablation strategy and predict outcome when using cryoballoon ablation.
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J et al. (2019) conducted a cohort in Persistent atrial fibrillation (n=148). Normal left atrial volume index (LAVI) was evaluated on Arrhythmia-free survival without the need for antiarrhythmic drug therapy. A normal left atrial volume index strongly predicted procedural success after cryoballoon ablation for persistent atrial fibrillation, achieving a 71.0% arrhythmia-free survival.
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