Why the study?
Differences in outcomes between coronary dominance patterns are increasingly recognized, warranting a summary of current understanding and literature gaps regarding anatomic, physiologic, and clinical implications.
Does left coronary dominance affect clinical outcomes in patients with ischemic, conduction, and valvular disease?
Does left coronary dominance affect clinical outcomes in patients with ischemic, conduction, and valvular disease?
This review highlights that left coronary dominance is associated with worse clinical outcomes in various cardiac disease states.
May warrant inclusion in prognostic models for ischemic, conduction, and valvular disease; hypothesis-generating and requires prospective validation.
Coronary dominance describes the anatomic variation of coronary arterial supply, notably as it relates to perfusion of the inferior cardiac territories. Differences in the development and outcome in select disease states between coronary dominance patterns are increasingly recognized. In particular, observational studies have identified higher prevalence of poor outcomes in left coronary dominance in the setting of ischemic, conduction, and valvular disease. In this qualitative literature review, we summarize anatomic, physiologic, and clinical implications of differences in coronary dominance to highlight current understanding and gaps in the literature that should warrant further studies.
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Wu et al. (2024) studied this question.
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