Torsemide Versus Furosemide in Heart Failure Patients
Why the study?
Does torsemide improve all-cause mortality compared to furosemide in patients admitted with heart failure?
Population
4,580 patients admitted with heart failure to Duke Hospital from 2000 to 2010
Comparison
Torsemide prescribed at discharge (n=625) vs Furosemide prescribed at discharge (n=3955)
Design
Cohort
Follow-up
5 years
Authors
Discussion
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Member takes
Implication
No mortality difference seen between torsemide and furosemide; leaves open whether randomized trials would alter diuretic choice in heart failure.
Structured PICO
Does torsemide improve all-cause mortality compared to furosemide in patients admitted with heart failure?
P
Population
4,580 patients admitted with heart failure to Duke Hospital from 2000 to 2010
I
Intervention
Torsemide prescribed at discharge (n=625)
C
Comparator
Furosemide prescribed at discharge (n=3955)
O
Outcome
All-cause mortality through 5 yearshard clinical
In a retrospective cohort of heart failure patients, discharge on torsemide versus furosemide showed no significant difference in 5-year all-cause mortality after risk adjustment.
Limitations
- potential for residual confounding
Cite This Study
Mentz et al. (2015) studied this question.