Why the study?
Is QT dispersion increased in patients with sickle cell disease, and what is the effect of pulmonary hypertension on QT dispersion?
Is QT dispersion increased in patients with sickle cell disease, and what is the effect of pulmonary hypertension on QT dispersion?
Sickle cell disease, particularly when complicated by pulmonary hypertension, is associated with increased QTc dispersion, suggesting regional inhomogeneity of ventricular repolarization.
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Increased QTc dispersion in SCD with PH should not change practice; hypothesis-generating for arrhythmia risk in prospective studies.
Akgül et al. (2007) studied this question.
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