Why the study?
Does acute reduction in ventricular volume via lower body negative pressure decrease QT interval dispersion in elderly men with and without heart failure?
Population
25 elderly men, comprising 14 with heart failure and 11 healthy controls.
Comparison
Lower body negative pressure applied at -15 and… vs Baseline measurements prior to LBNP application.
Design
Other
Follow-up
15 minutes
Authors
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Supports volume dependence of QT dispersion over autonomic tone; hypothesis-generating for arrhythmia risk in HF.
Does acute reduction in ventricular volume via lower body negative pressure decrease QT interval dispersion in elderly men with and without heart failure?
Acute reduction in ventricular volume decreases QT interval dispersion in elderly men, suggesting that altered QT dispersion is more closely related to changes in ventricular volume than to autonomic nervous system activity.
Carvalho et al. (2004) studied this question.
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