Population
10 patients with mild cognitive impairment (MCI)
Design
Cohort
Follow-up
minimum of 6 years
Authors
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Small MCI cohort showed universal dementia progression; hypothesis-generating and requires larger prospective validation before informing prognosis.
In patients with mild cognitive impairment, progression to full-blown dementia was universal over a minimum 6-year follow-up, though the rate and sequence of cognitive decline varied.
Hodges et al. (2006) studied this question.
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