Key Points
- To assess 20-year trends in attack rate, incidence of non-fatal myocardial infarction, and coronary heart disease mortality in individuals aged 64 years and younger.
- Analyzed longitudinal surveillance data from the Göteborg myocardial infarction register covering the years 1975 through 1994.
- Tracked attack rates, non-fatal incidence, 28-day case fatality, and treatment interventions using standardized diagnostic criteria across consistent age strata.
- Attack rate and incidence decreased significantly by 2.1% to 3.9% per year across most age groups, remaining 3-5 times higher in men than in women.
- Coronary heart disease mortality declined by 2.0% to 6.8% per year, with 28-day case fatality declining significantly primarily in the oldest male group (aged 55-64).
- In-hospital administration of intravenous beta-blockers, nitroglycerin, and thrombolytics rose over time, while the majority of fatal events continued to occur pre-hospital in individuals without diagnosed heart disease.
Structured PICO
PPopulationPersons aged 64 and below in Goteborg, Sweden, during the period 1975-1994
OOutcomeTrends in attack rate, incidence of non-fatal myocardial infarction, and mortality from coronary heart diseasehard clinical
Coronary heart disease attack rate, incidence, and mortality significantly decreased in Sweden between 1975 and 1994 among individuals aged 64 and below.