What does this research mean for the field?

A more than 50% decline in the attack rate of acute myocardial infarction over 30 years is comparable with and accurately predicted by the decline in multivariable cardiovascular risk factors. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study aims to explore the relationship between changes in cardiovascular risk factors and the attack rate of acute myocardial infarction (AMI) in men aged 50.

February 21, 2008Journal of Internal MedicineOpen Access

Secular changes in cardiovascular risk factors and attack rate of myocardial infarction among men aged 50 in Gothenburg, Sweden. Accurate prediction using risk models

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Acute myocardial infarction. Intervention: Secular changes in cardiovascular risk factors vs. Historical baseline (1963). Primary outcome: Attack rate of acute myocardial infarction (AMI).

View Full Paper

Ask AI

Bookmark

Key result

A more than 50% decline in the attack rate of acute myocardial infarction over 30 years was comparable with the decline in multivariable cardiovascular risk factors.

Key Points

This study aims to explore the relationship between changes in cardiovascular risk factors and the attack rate of acute myocardial infarction (AMI) in men aged 50.
Examined cross-sectional population samples of 50-year-old men every 10 years from 1963 to 2003.
Recorded attack rates of AMI from 1975 to 2004.
Analyzed changes in prevalence of smoking, BMI, diabetes, blood pressure, and cholesterol over time.
Smoking prevalence decreased from 56% in 1963 to 22% in 2003.
AMI attack rates declined by 45% from 1975-1979 to 2000-2004 in three age groups: 35-44, 45-54, and 55-64.
28-day case fatality rates fell from 30%, 38%, and 46% to 12%, 16%, and 20% across the same age groups, respectively.

Study Design

Type

Cross-Sectional

Multicenter

Structured PICO

Population

50-year-old men in Gothenburg, Sweden, examined in cross-sectional population samples every 10th year from 1963 to 2003.

Outcome

Attack rate of acute myocardial infarction (AMI) and changes in cardiovascular risk factorshard clinical

A more than 50% decline in the attack rate of acute myocardial infarction over 30 years in Swedish men closely paralleled secular improvements in major cardiovascular risk factors.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Encourages ongoing population risk factor control; leaves open causal links from observational trends.

Cite This Study

Wilhelmsen et al. (2008) conducted a cross-sectional in Acute myocardial infarction. Secular changes in cardiovascular risk factors vs. Historical baseline (1963) was evaluated on Attack rate of acute myocardial infarction (AMI). A more than 50% decline in the attack rate of acute myocardial infarction over 30 years was comparable with the decline in multivariable cardiovascular risk factors.

synapsesocial.com/papers/6a1adaa35448f1e38b461fb7 https://doi.org/10.1111/j.1365-2796.2008.01931.x

View Full Paper

Ask AI

Bookmark

Secular changes in cardiovascular risk factors and attack rate of myocardial infarction among men aged 50 in Gothenburg, Sweden. Accurate prediction using risk models

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Secular changes in cardiovascular risk factors and attack rate of myocardial infarction among men aged 50 in Gothenburg, Sweden. Accurate prediction using risk models

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider