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July 26, 2024Frontiers in Cardiovascular MedicineOpen Access

Cardioneuroablation: the known and the unknown

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Why the study?

Clinical data regarding cardioneuroablation are limited, and expert consensus or guideline recommendations for this technique are lacking.

Does cardioneuroablation improve outcomes in young patients with recurrent vasovagal syncope and advanced atrioventricular block?

Design

Review

Authors

AMA MarreseAgaplesion Markus HospitalRPRiccardo PersicoUniversity of Naples Federico IIEPEmanuele ParlatoUniversity of Naples Federico II

Discussion

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Overview

Cardioneuroablation should not yet alter practice in recurrent vasovagal syncope; leaves open the need for prospective trials to inform guidelines.

Structured PICO

Does cardioneuroablation improve outcomes in young patients with recurrent vasovagal syncope and advanced atrioventricular block?

P
Population
Young patients with recurrent vasovagal syncope (VVS) and advanced atrioventricular block secondary to hyperactivation of vagal tone
I
Intervention
Cardioneuroablation (CNA)

Cardioneuroablation is a novel procedure for recurrent vasovagal syncope and AV block in young patients, but clinical data remain limited and guideline recommendations are lacking.

Limitations

  • clinical data are still limited
  • expert consensus or recommendations in the guidelines regarding this technique are still lacking

Cite This Study

Marrese et al. (2024) studied this question.

synapsesocial.com/papers/6a0fcf2f57bfcc72645fbb3fhttps://doi.org/10.3389/fcvm.2024.1412195
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1“Cardioneuroablation” – new treatment for neurocardiogenic syncope, functional AV block and sinus dysfunction using catheter RF-ablation2005 · 353 citations
  2. 2Procedural and Intermediate-term Results of the Electroanatomical-guided Cardioneuroablation for the Treatment of Supra-Hisian Second- or Advanced-degree Atrioventricular Block: the PIRECNA multicentre registry2024 · 22 citations
  3. 3Selective Atrial Vagal Denervation Guided by Evoked Vagal Reflex to Treat Patients With Paroxysmal Atrial Fibrillation2006 · 285 citations
  4. 4The benefit of pacemaker therapy in patients with neurally mediated syncope and documented asystole: a meta-analysis of implantable loop recorder studies2017 · 47 citations
  5. 5Distribution of adrenergic and cholinergic nerve fibres within intrinsic nerves at the level of the human heart hilum2013 · 32 citations