Why the study?
Clinical data regarding cardioneuroablation are limited, and expert consensus or guideline recommendations for this technique are lacking.
Does cardioneuroablation improve outcomes in young patients with recurrent vasovagal syncope and advanced atrioventricular block?
Does cardioneuroablation improve outcomes in young patients with recurrent vasovagal syncope and advanced atrioventricular block?
Cardioneuroablation is a novel procedure for recurrent vasovagal syncope and AV block in young patients, but clinical data remain limited and guideline recommendations are lacking.
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Cardioneuroablation should not yet alter practice in recurrent vasovagal syncope; leaves open the need for prospective trials to inform guidelines.
Cardioneuroablation (CNA) is a novel interventional procedure for the treatment of recurrent vasovagal syncope (VVS) and advanced atrioventricular block secondary to hyperactivation of vagal tone in young patients. By damaging the cardiac parasympathetic ganglia, CNA seems to be able to mitigate and/or abolish the excessive vagal activity and improve patients' outcome. This review is intended to give a detailed and comprehensive overview of the current evidences regarding (1) the clinical applications of CNA (2) the identification of ablation targets and procedural endpoints (3) the medium-long term effect of the procedure and its future perspectives. However, clinical data are still limited, and expert consensus or recommendations in the guidelines regarding this technique are still lacking.
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Marrese et al. (2024) studied this question.
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