Why the study?
Cardioneuroablation is emerging as an appealing treatment for vasovagal syncope, but procedural protocols require standardization and long-term pathophysiological effects remain unclear.
Does cardioneuroablation improve outcomes in patients with vasovagal reflex syncope?
Does cardioneuroablation improve outcomes in patients with vasovagal reflex syncope?
Cardioneuroablation is an emerging therapeutic option for vasovagal syncope, though standardized protocols and long-term safety data are still needed.
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Should not yet change practice in vasovagal syncope; leaves open standardization and long-term safety assessment.
Cardioneuroablation (CNA) is emerging as an appealing therapeutic option for patients with vasovagal reflex syncope. This review examines key aspects of CNA, including patient selection, procedural aspects and mid-term effects. We critically evaluate procedural results from recent studies and address ongoing challenges, such as the need for standardized procedural protocols and harmonized postprocedural data collection. In addition, we outline current gaps in knowledge concerning long-term pathophysiological effects of the procedure, in particular regarding ventricular arrhythmia susceptibility and exercise capacity.
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Saglietto et al. (2025) studied this question.
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