Why the study?
Does leisure-time physical activity improve endothelial function and reduce aortic intima-media thickness progression in healthy adolescents?
Population
Healthy adolescents participating in a longitudinal atherosclerosis prevention study, n=553 at age 13, n=531…
Comparison
Leisure-time physical activity vs Sedentary lifestyle or lower levels of physical…
Design
Cohort
Follow-up
4 years (from age 13 to 17)
Authors
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Supports activity counseling in adolescents but should not yet change practice; extends observational data, leaving causality open for RCTs.
Does leisure-time physical activity improve endothelial function and reduce aortic intima-media thickness progression in healthy adolescents?
A physically active lifestyle in adolescence is associated with improved endothelial function and attenuated progression of aortic intima-media thickness, highlighting its role in early atherosclerosis prevention.
Pahkala et al. (2011) studied this question.
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