Why the study?
PVI alone for persistent AF remains controversial, and the characteristics of cryoballoon ablation to treat persistent AF along with blanking period recurrence are underreported.
What are the risk factors for recurrence after second-generation cryoballoon ablation for de novo pulmonary vein isolation in patients with persistent atrial fibrillation?
What are the risk factors for recurrence after second-generation cryoballoon ablation for de novo pulmonary vein isolation in patients with persistent atrial fibrillation?
In patients with persistent AF undergoing cryoballoon ablation, longer AF duration and larger left atrial size are significant risk factors for recurrence.
BACKGROUND: Pulmonary vein isolation (PVI) alone for persistent atrial fibrillation (PersAF) remains controversial. The characteristics of cryoballoon ablation (CBA) to treat PersAF and the blanking period recurrence are underreported. METHODS: This study retrospectively analyzed patients with PersAF undergoing second-generation CBA for de novo PVI. The post-procedural efficacy and survival analysis were compared between patients with different PersAF durations. The multivariate Cox regression analysis was used to detect the risk factors for recurrence. Early and long-term recurrence were analyzed relative to each other. RESULTS: < 0.0001). CONCLUSIONS: CBA of PersAF had safety and efficacy to reach de novo PVI. The PersAF duration and left atrial size were risk factors for atrial fibrillation recurrence after CBA. Blanking period recurrence was associated with long-term recurrence.
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Cao et al. (2022) studied this question.
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