Key result
Lipid raft signalling plays an important role in the pathogenesis of various conditions, including cardiovascular and neurodegenerative diseases, making these membrane domains potential pharmacological targets.
Design
Review
Authors
Loading...
Should not yet change cardiovascular practice; leaves open therapeutic targeting of lipid rafts for future trials.
Lipid rafts and caveolae represent important signaling platforms whose dysregulation is implicated in multiple diseases, offering potential targets for pharmacological intervention.
Michel et al. (2007) conducted a review in Various diseases (Alzheimer's, Parkinson's, cardiovascular, prion diseases, systemic lupus erythematosus, HIV). Lipid rafts and caveolae was evaluated. Lipid raft signalling plays an important role in the pathogenesis of various conditions, including cardiovascular and neurodegenerative diseases, making these membrane domains potential pharmacological targets.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: