Key result
Caveolin-1 is an essential structural component of cell surface caveolae that plays a key role in cellular signaling and the development of diseases such as cancer.
Design
Review
Authors
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Does not support clinical adoption in cancer; leaves open caveolin-1 targeting for prospective trials.
This review highlights the structural and functional roles of caveolins and lipid rafts in cellular signaling and disease pathogenesis, particularly cancer.
Quest et al. (2004) conducted a review in Cancer and cellular signaling diseases. Caveolin-1 was evaluated. Caveolin-1 is an essential structural component of cell surface caveolae that plays a key role in cellular signaling and the development of diseases such as cancer.
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