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April 20, 2004AJP Heart and Circulatory Physiology37 citations

Evaluating Left Atrial Stiffness and Mitral Deceleration Time Post-Cardiopulmonary Bypass

Early mitral deceleration and left atrial stiffness

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Why the study?

Does left atrial stiffness affect the estimation of left ventricular stiffness from Doppler deceleration time?

Population

15 patients assessed immediately after cardiopulmonary bypass

Design

Other

Authors

PMPaolo MarinoGFGiuseppe FaggianPBPaolo Bertolini

Discussion

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Overview

May support Doppler DT for LV stiffness estimation without LA adjustment; leaves open broader validation.

Key Points

  • The study aims to quantify left atrial stiffness (KLA) during deceleration time (DT) and assess its impact on left ventricular stiffness (KLV).
  • Assessed LV stiffness (KLV) using mitral tracings from transesophageal echocardiography after cardiopulmonary bypass.
  • Obtained LA volume curve and measured time-adjusted LA pressure simultaneously with Doppler data in 15 patients.
  • Calculated KLA during the ascending limb of the V loop and during DT.
  • LA volume decreased by 7.3 +/- 6.5 ml/m2 during the first mitral DT (P < 0.001).
  • KLV averaged 0.25 +/- 0.32 mmHg/ml, indicating it can be assessed noninvasively from DT.
  • KLA during DT was close to zero, averaging -0.001 +/- 0.031 mmHg/ml (not significant).

Structured PICO

Does left atrial stiffness affect the estimation of left ventricular stiffness from Doppler deceleration time?

P
Population
15 patients assessed immediately after cardiopulmonary bypass
I
Intervention
Transesophageal echocardiography and simultaneous time-adjusted left atrial pressure measurement
O
Outcome
Left atrial stiffness (KLA) during the deceleration time (DT)surrogate

Left atrial stiffness is close to zero during deceleration time and does not confound the noninvasive estimation of left ventricular stiffness using Doppler echocardiography.

Cite This Study

Marino et al. (2004) studied this question.

synapsesocial.com/papers/6a0fddf35725bbd5cc602ca8https://doi.org/10.1152/ajpheart.00051.2004
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