Primary prevention of type 2 diabetes:A review of the current state

The prevalence of Type 2 diabetes is increasing globally. It is the cause of significant mortality and morbidity due to the development of microand macrovascular complications. It can cause blindness, end-stage renal disease, and lower extremity amputations and is also a major risk factor for myocardial infarction and stroke. Macrovascular disease and its risk factors are often already present in patients with impaired glucose tolerance (IGT) and impaired fasting glucose (IFG), suggesting that an additional benefit of an intervention before the diagnosis of diabetes, may be to prevent the progression of the macrovascular disease.