Key result
Heart rate variability measures are linked to LV systolic function in healthy individuals.
Why the study?
The study evaluated the relationship between heart rate variability and echocardiography indices of cardiac function in healthy individuals.
Cross-Sectional (n=30)
Effect estimate: r = -0.47 (HF and LV-GLS), r = -0.39 (RMSSD and LVEF)
p-value: p=0.01 and 0.03
In healthy individuals, heart rate variability measures such as high frequency power and RMSSD are significantly associated with left ventricular systolic function indices.
HRV-LV function associations should not change practice; hypothesis-generating and requires prospective validation.
Purpose This study evaluated the relationship between HRV and echocardiography indices of cardiac function. Methods Healthy individuals ( N = 30) aged 33 ± 10 years old, underwent short‐term resting HRV assessment and transthoracic echocardiography with speckle tracking analysis. Time domain ‐ (i.e. R‐R interval, root mean square of successive RR interval difference (RMSSD), standard deviation of normal RR intervals (SDNN) and frequency domain‐measures of HRV (i.e. high‐frequency power (HF), low‐frequency power (LF), high‐frequency normalised (HFnorm) and low‐frequency normalised (LFnorm)). Echocardiography indices of cardiac function included; Left ventricular ejection fraction (LVEF), left‐ and right‐ventricular global longitudinal strain (LV‐GLS, and RV GLS), left atrial strain: left atrial reservoir (LA res ), left atrial conduit (LA con ) and left atrial contraction (LA CT ). Results The mean values for HRV time‐domain measures were: R‐R (991 ± 176 ms), SDNN (50.9 ± 21.5 ms), and RMSSD (46.8 ± 29.4 ms); and frequency‐domain: LF (727 ± 606 ms 2 ), HF (415 ± 35 ms 2 ), LFnorm (56 ± 19.4) and HFnorm (36.5 ± 18.8). Mean values for indices of cardiac function were LVEF (59.9% ± 2.8%), LV‐GLS (19.2% ± 1.4%), RV‐GLS (21.7% ± 2.7%), LA res (36.8% ± 6.99%), LA con (26.2% ± 6.95%) and LA CT (12.3% ± 3.56%). There was a significant negative relationship between HF and LV‐GLS ( r = −0.47, p = 0.01) and RMSSD and LVEF ( r = −0.39, p = 0.03) respectively. Conclusion Heart rate variability measures such as high frequency power and RMSSD are associated with left ventricle systolic function in healthy individuals.
No takes yet. Share an insight, caveat, or question.
Rahman et al. (2024) conducted a cross-sectional in Healthy individuals (n=30). Heart rate variability assessment was evaluated on Relationship between HRV and echocardiography indices of cardiac function (r = -0.47 (HF and LV-GLS), r = -0.39 (RMSSD and LVEF), p=0.01 and 0.03). Heart rate variability measures such as high-frequency power and RMSSD were significantly associated with left ventricle systolic function in healthy individuals (r=-0.47, p=0.01 and r=-0.39, p=0.03).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: