Key result
A newly isolated 175-kDa membrane protein from chicken gizzard smooth muscle localizes near the plasma membrane and interacts specifically with vinculin.
Population
Chicken gizzard smooth muscle and cardiac muscle
Design
Preclinical
Authors
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May indicate a vinculin partner in muscle membrane linkage; hypothesis-generating for cardiac roles and needs mammalian validation.
A newly isolated 175-kDa membrane protein localizes near the plasma membrane in smooth and cardiac muscles and interacts with vinculin, suggesting a role in connecting microfilaments to the cell membrane.
Koteliansky et al. (1985) studied this question. A newly isolated 175-kDa membrane protein from chicken gizzard smooth muscle localizes near the plasma membrane and interacts specifically with vinculin.
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