Why the study?
Does pravastatin improve carotid intima-media thickness and is it safe in children with familial hypercholesterolemia?
Does pravastatin improve carotid intima-media thickness and is it safe in children with familial hypercholesterolemia?
Two years of pravastatin therapy safely induces regression of carotid atherosclerosis in children with familial hypercholesterolemia without adverse effects on growth or sexual maturation.
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Supports early pravastatin in pediatric familial hypercholesterolemia; extends carotid atherosclerosis regression evidence to children.
Wiegman et al. (2004) studied this question.
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