Why the study?
Does obstructive sleep apnea impair baroreflex sensitivity to a hypotensive stimulus compared to matched controls?
Does obstructive sleep apnea impair baroreflex sensitivity to a hypotensive stimulus compared to matched controls?
Patients with obstructive sleep apnea exhibit impaired cardiac and sympathetic baroreflex sensitivity to hypotensive stimuli, which may contribute to augmented resting sympathetic activity.
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Impaired baroreflex sensitivity may heighten sympathetic activity in OSA; hypothesis-generating for causal mechanisms and interventions.
Carlson et al. (1996) studied this question.
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