Key result
Diabetes increases the risk of atherosclerotic vascular disease through mechanisms that remain largely unexplained and are only partially mediated by conventional risk factors.
Conventional risk factors like lipids and hypertension only partially explain the increased risk of atherosclerotic cardiovascular disease in diabetic patients.
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Intensified conventional risk factor control remains warranted in diabetes; leaves open identification of unexplained mechanisms for targeted therapies.
Pyörälà et al. (1987) conducted a review in Diabetes and atherosclerosis. Diabetes increases the risk of atherosclerotic vascular disease through mechanisms that remain largely unexplained and are only partially mediated by conventional risk factors.
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