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January 1, 1999Clinical and Experimental Hypertension

Accelerated atherosclerosis in diabetes is driven by mechanisms unique to diabetes such as non-enzymatic glycation of proteins, oxidative modification of lipoproteins, and insulin resistance.

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Population

Individuals with diabetes mellitus and hypertension

Design

Review

Authors

VSV. Shantaram

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Overview

May support intensified multifactorial risk control in diabetes; leaves open dominant pathway prioritization for targeted therapies.

Structured PICO

P
Population
Individuals with diabetes mellitus and hypertension

The review highlights the unique pathogenic mechanisms of atherosclerosis in diabetes and hypertension, emphasizing the need for comprehensive risk factor management including tight control of hyperglycemia, hypertension, and hyperlipidemia.

Cite This Study

V. Shantaram (1999) studied this question.

synapsesocial.com/papers/6a7e588a567bd3ec6fb7b2ddhttps://doi.org/10.3109/10641969909068650
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diabetes and atherosclerosis: An epidemiologic view1987 · 923 citations
  2. 2Pathogenesis of atherosclerosis in peripheral artery disease for diabetes patients2020 · 2 citations
  3. 3Insulin Resistance, Hyperinsulinemia, Dyslipidemia, Hypertension, and Accelerated Atherosclerosis1992 · 69 citations
  4. 4Atherosclerosis and Hypertension1990 · 75 citations
  5. 5Atherosclerosis and Hypertension1990 · 22 citations