Population
Patients with diabetes and peripheral artery disease (PAD)
Design
Review
Key result
Diabetes mellitus accelerates the pathogenesis of atherosclerosis in peripheral artery disease through mechanisms involving endothelial dysfunction, dyslipidemia, inflammation, and increased platelet activity.
Authors
Loading...
May support intensified risk factor control in diabetic PAD; leaves open prospective validation of mechanism-specific therapies.
This review highlights the pathogenesis of atherosclerosis in diabetic patients with PAD and emphasizes the importance of risk factor reduction to prevent atherothrombotic episodes.
Andrei et al. (2020) conducted a review in Peripheral artery disease in diabetes mellitus. Diabetes mellitus and associated risk factors was evaluated. Diabetes mellitus accelerates the pathogenesis of atherosclerosis in peripheral artery disease through mechanisms involving endothelial dysfunction, dyslipidemia, inflammation, and increased platelet activity.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: