Why the study?
PAD patients with DM have a significantly higher rate of major adverse cardiovascular events, all-cause mortality, and limb amputation compared with patients with PAD alone, making aggressive diagnosis and management critical.
Population
Patients with peripheral artery disease (PAD) and diabetes mellitus (DM)
Design
Review
Authors
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Emphasizes aggressive CV risk management in diabetic PAD; leaves open optimal regimens pending prospective trials.
Aggressive diagnosis and pharmacological management of PAD in patients with diabetes is crucial to prevent major adverse cardiovascular events and limb amputation.
Suk Chon (2019) studied this question.