CT-Derived Body Fat Distribution and Incident Cardiovascular Disease: The Multi-Ethnic Study of Atherosclerosis
Why the study?
Is CT-derived visceral or subcutaneous fat independently associated with incident cardiovascular disease and all-cause mortality in a multiethnic cohort?
Population
1910 participants from the Multi-Ethnic Study of Atherosclerosis with abdominal fat measurements from…
Comparison
Higher tertiles of CT-derived visceral and… vs Lower tertiles of CT-derived visceral and…
Design
Cohort
Follow-up
average 9.3 years
Authors
Discussion
Loading...
Member takes
Implication
Visceral fat may refine CVD risk assessment beyond BMI; leaves open whether targeting it improves outcomes.
Structured PICO
Is CT-derived visceral or subcutaneous fat independently associated with incident cardiovascular disease and all-cause mortality in a multiethnic cohort?
P
Population
1910 participants from the Multi-Ethnic Study of Atherosclerosis with abdominal fat measurements from computed tomography scans, mean age 65 years, 50% female, multiethnic (21% African American, 13% Asian, 26% Hispanic).
I
Intervention
Higher tertiles of CT-derived visceral and subcutaneous fat
C
Comparator
Lower tertiles of CT-derived visceral and subcutaneous fat
O
Outcome
Incident cardiovascular disease (CVD) and all-cause mortalityhard clinical
Visceral fat, but not subcutaneous fat, is independently associated with an increased risk of incident cardiovascular disease, highlighting the importance of fat distribution in cardiometabolic risk assessment.
Cite This Study
Mongraw‐Chaffin et al. (2017) studied this question.