August 1, 1998Diabetic Medicine
Comparison of prevalence and risk factors for microalbuminuria in South Asians and Europeans with Type 2 diabetes mellitus
Key result
South Asian ethnicity was associated with a higher prevalence of microalbuminuria compared to European ethnicity in Type 2 diabetes patients (adjusted OR 2.07; 95% CI 1.13-3.79; p=0.02).
Why the study?
Does South Asian ethnicity increase the prevalence of microalbuminuria in patients with Type 2 diabetes mellitus compared to European ethnicity?
Population
1,472 Type 2 diabetes mellitus clinic attenders (583 European and 889 South Asian) at Ealing Hospital, London
Comparison
South Asian ethnicity vs European ethnicity
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May inform ethnicity-specific microalbuminuria risk assessment in T2DM; hypothesis-generating and requires prospective validation.
Study Design
Type
Cross-Sectional (n=1,472)
Multicenter
No
Structured PICO
Does South Asian ethnicity increase the prevalence of microalbuminuria in patients with Type 2 diabetes mellitus compared to European ethnicity?
P
Population
1,472 Type 2 diabetes mellitus clinic attenders (583 European and 889 South Asian) at Ealing Hospital, London
I
Intervention
South Asian ethnicity
C
Comparator
European ethnicity
O
Outcome
Prevalence of microalbuminuria (measured by albumin/creatinine ratios in early morning urines)surrogate
Main Result
Effect estimate: OR 2.07 (95% CI 1.13-3.79)
p-value: p=0.02
South Asian patients with Type 2 diabetes have a significantly higher prevalence of microalbuminuria compared to European patients, a difference not fully explained by traditional risk factors.
Cite This Study
Mather et al. (1998) conducted a cross-sectional in Type 2 diabetes mellitus (n=1,472). South Asian ethnicity vs. European ethnicity was evaluated on Prevalence of microalbuminuria (OR 2.07, 95% CI 1.13-3.79, p=0.02). South Asian ethnicity was associated with a higher prevalence of microalbuminuria compared to European ethnicity in Type 2 diabetes patients (adjusted OR 2.07; 95% CI 1.13-3.79; p=0.02).