Why the study?
Lesion Index (LSI) was developed to predict lesion efficacy during RF catheter ablation, but its value in predicting lesion size remained to be established.
Does the Lesion Index (LSI) accurately predict lesion size and depth during radiofrequency catheter ablation in an in vivo beating heart?
Population
64 myocardial lesions created in an in vivo beating heart
Comparison
Prespecified LSI values (LSI = 4 vs 5 vs 6) during RF delivery
Design
In vivo preclinical validation study
Authors
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Supports LSI for lesion prediction in beating-heart models; leaves open human validation before clinical use.
Does the Lesion Index (LSI) accurately predict lesion size and depth during radiofrequency catheter ablation in an in vivo beating heart?
In an in vivo model, the Lesion Index (LSI) during radiofrequency catheter ablation strongly predicts myocardial lesion width and depth.
Themistoclakis et al. (2022) studied this question.
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