February 24, 2020Pacing and Clinical Electrophysiology
The force stability of tissue contact and lesion size index during radiofrequency ablation: An ex‐vivo study
Key result
The force stability of catheter contact had no relevant impact on lesion width or depth during LSI-guided radiofrequency ablation in an ex-vivo model.
Why the study?
Whether the force stability of tissue contact influences lesion size during lesion size index (LSI)-guided radiofrequency ablation was unknown.
Does the force stability of tissue contact influence lesion size during LSI-guided radiofrequency ablation in an ex-vivo porcine model?
Population
267 RF lesions across 6 porcine hearts
Comparison
Intermittent vs variable vs constant tissue contact across catheter orientations and target LSIs
Design
Ex-vivo experimental study
Authors
Discussion
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Member takes
Implication
Force stability need not dictate LSI-guided ablation technique; leaves open in-vivo validation.
Structured PICO
Does the force stability of tissue contact influence lesion size during LSI-guided radiofrequency ablation in an ex-vivo porcine model?
P
Population
267 radiofrequency lesions created on 6 ex-vivo porcine myocardial slabs to evaluate the influence of force stability on lesion size.
I
Intervention
Radiofrequency ablation (35 W) using an open-tip irrigated catheter with intermittent (0-20 g) or variable (10-20 g) tissue contact, applied perpendicularly or parallelly up to a target Lesion Size Index (LSI) of 5 or 6
C
Comparator
Radiofrequency ablation with constant tissue contact (15 g) up to the same target LSI
O
Outcome
Lesion width and depthsurrogate
In LSI-guided radiofrequency ablation, maintaining constant contact force does not significantly alter lesion dimensions compared to variable or intermittent contact, provided the target LSI is reached.
Cite This Study
Parwani et al. (2020) studied this question. Force stability of tissue contact (intermittent, variable, or constant) vs. Constant tissue contact was evaluated on Lesion width and depth. The force stability of catheter contact had no relevant impact on lesion width or depth during LSI-guided radiofrequency ablation in an ex-vivo model.