Why the study?
Does cardiac resynchronization therapy (CRT) reduce the incidence of atrial fibrillation in patients with moderate or severe heart failure?
Population
813 patients with moderate or severe heart failure
Comparison
Cardiac resynchronization therapy added to… vs Pharmacological therapy alone
Design
RCT, Randomly assigned
Follow-up
mean 29.4 months
Authors
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CRT confers no reduction in new-onset AF in moderate-to-severe HF; confirms neutral effect on atrial arrhythmias while preserving ventricular outcome benefits.
Does cardiac resynchronization therapy (CRT) reduce the incidence of atrial fibrillation in patients with moderate or severe heart failure?
CRT does not reduce the incidence of new-onset atrial fibrillation in patients with moderate to severe heart failure, but it remains effective at improving outcomes regardless of AF development.
Hoppe et al. (2006) studied this question.
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