What question did this study set out to answer?

The study aims to identify circulating dengue serotypes in dengue-positive cases and to assess the relationship between serotype and disease severity.

May 22, 2026Frontiers in Tropical DiseasesOpen Access

Circulating dengue virus serotypes in central India: a molecular surveillance study

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Authors

VSVishal SheteAll India Institute of Medical Sciences MMMeena MishraGovernment Medical College NTNitali TadkalkarICMR-National Institute of Virology

Discussion

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Implication

Randomized trial explores dengue serotypes and disease severity in central India, highlighting key findings on viral circulation.

Key Points

The study aims to identify circulating dengue serotypes in dengue-positive cases and to assess the relationship between serotype and disease severity.
Collected acute-phase samples within 5 days post-disease onset for NS1 ELISA and serotyping.
Performed DENV IgM ELISA for late-phase samples and used RT-PCR for detecting DENV RNA.
Conducted serotype analysis on DENV RNA-positive samples.
DENV-2 was the predominant serotype at 50% of cases, alongside DENV-1 and DENV-3.
27% of cases exhibited hybrid serotype infections, indicating multiple serotype circulation.
Clinical recovery was noted in 83.3% of patients, with a median hospital stay of 7 days.

Cite This Study

Shete et al. (2026) studied this question.

synapsesocial.com/papers/6a0ff1dbd674f7c03778b0da https://doi.org/10.3389/fitd.2026.1822411

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May 22, 2026Frontiers in Tropical DiseasesOpen Access

Circulating dengue virus serotypes in central India: a molecular surveillance study

View Full Paper

Ask AI

Bookmark

Authors

VSVishal SheteAll India Institute of Medical Sciences MMMeena MishraGovernment Medical College NTNitali TadkalkarICMR-National Institute of Virology

Discussion

Member takes

Implication

Randomized trial explores dengue serotypes and disease severity in central India, highlighting key findings on viral circulation.

Key Points

The study aims to identify circulating dengue serotypes in dengue-positive cases and to assess the relationship between serotype and disease severity.
Collected acute-phase samples within 5 days post-disease onset for NS1 ELISA and serotyping.
Performed DENV IgM ELISA for late-phase samples and used RT-PCR for detecting DENV RNA.
Conducted serotype analysis on DENV RNA-positive samples.
DENV-2 was the predominant serotype at 50% of cases, alongside DENV-1 and DENV-3.
27% of cases exhibited hybrid serotype infections, indicating multiple serotype circulation.
Clinical recovery was noted in 83.3% of patients, with a median hospital stay of 7 days.

Cite This Study

Shete et al. (2026) studied this question.

synapsesocial.com/papers/6a0ff1dbd674f7c03778b0da https://doi.org/10.3389/fitd.2026.1822411

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