Why the study?
Data on the long-term outcomes and procedural details of the lesion size index-guided high-power ablation strategy (HP-LSI) are limited.
Does high power LSI-guided ablation reduce 1-year AF recurrence compared to time-restricted high-power ablation in patients with paroxysmal atrial fibrillation?
Does high power LSI-guided ablation reduce 1-year AF recurrence compared to time-restricted high-power ablation in patients with paroxysmal atrial fibrillation?
Lesion size index-guided high-power ablation significantly reduces 1-year AF recurrence and improves procedural efficiency compared to time-restricted high-power ablation for pulmonary vein isolation.
Supports LSI-guided high-power PVI in paroxysmal AF; leaves open confirmation in randomized trials before practice change.
Introduction: Data on the long-term outcomes and procedural details of the lesion size index-guided high-power ablation strategy (HP-LSI) are limited. Methods: Eighty patients were retrospectively assigned to the high-power with time-restricted ablation strategy (fixed at 10 s per lesion), while 67 patients were assigned to the high power LSI-guided strategy (anterior wall LSI at least 5.0, posterior wall LSI 4.5). The 1-year AF recurrence rate and various procedural details were compared between the two groups. Results: = 0.016). Additionally, fewer gaps were identified in various PV segments in the HP-LSI group following the initial pass of PV circumferential ablation. The radiofrequency time, LA dwelling time, and skin-to-skin time were shorter, and the first-pass isolation rates for both pulmonary veins were higher in the HP-LSI group. Conclusion: The HP-LSI ablation strategy is associated with a significantly lower AF recurrence rate and improved procedural efficiency, suggesting its potential as a preferred strategy for PVI.
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Kuo et al. (2025) studied this question.
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