Systematic review assesses soft tissue changes in dementia, highlighting biomarker potential and correlations with cognitive decline.
• TMT is a viable biomarker for sarcopenia in dementia imaging. • Craniofacial muscle loss correlates with cognitive impairment. • Muscle fat infiltration links to brain atrophy in AD and DLB. • Sarcopenia and dementia share metabolic and inflammatory pathways.
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Pipitone et al. (2026) studied this question.
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