Study reconstructs genetic systems logic in a novel gene editing paradigm, suggesting a transformative approach.
Traditional gene editing technologies are fundamentally constrained by linear cognitive frameworks in three-dimensional space and fragmented gene regulation models, leading to inherently unresolvable flaws such as off-target effects, target site limitations, and systemic life-system imbalances. This paper reconstructs the underlying operational logic of genetic systems based on the four core laws of Yuanxian Theory (YXT) and the T64 compact torus spacetime model. Yuanxian Theory decrees that the universe is an autopoietic, self-referential, and self-consistent living organism, within which the genome manifests as a microscopic holographic subsystem. We rigorously prove the holographic coupling between the T64 high-dimensional topological structure and genomic encoding, expression, mutation, and repair processes. Consequently, we construct a high-dimensional gene editing theoretical framework governed by the four fundamental laws: True-Circle Self-Consistency (TCSC), Factor Conservation of the System (FSC), Spacetime Uniqueness Mechanism (STM), and Self-Referential Mind-Field Generation (SRM). Furthermore, we propose a T64 dimension-adaptive gene editing paradigm, realizing a radical transition from localized sequence cutting to global topological optimization. This paradigm establishes four core editing principles (True-Circle Self-Consistency Priority, Cosmic Factor Conservation, T64 Dimension-Adaptivity, and Self-Referential Dynamic Co-evolution) and outlines a technical implementation pathway encompassing high-dimensional target selection, scarless self-consistent editing, factor equilibrium regulation, and dynamic self-referential feedback. All core mathematical derivations have been formally verified within the Lean 4 theorem prover.
No takes yet. Share an insight, caveat, or question.
Zhenyuan Acharya (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: