Key result
Targeted ablation renders scar-related VT noninducible in a pacemaker-dependent patient with 0 recurrent events.
Why the study?
Ventricular tachycardia typically presents with wide QRS complexes, making narrow QRS tachycardia in pacemaker-dependent patients a diagnostic challenge.
Case Report (n=1)
Ventricular tachycardia can present with a narrow QRS complex in pacemaker-dependent patients when the reentrant circuit is near the His-Purkinje system, and it can be successfully treated with targeted ablation.
May inform select narrow QRS VT cases; leaves open need for prospective validation before practice change.
BACKGROUND: Ventricular tachycardia (VT) is typically associated with wide QRS complexes; therefore, narrow QRS tachycardia in pacemaker-dependent patients represents a diagnostic challenge. CASE SUMMARY: We report a 79-year-old man with permanent atrial fibrillation and complete atrioventricular block who presented with a regular narrow QRS tachycardia. Device interrogation confirmed ventricular pacing dependence. Electrophysiological studies demonstrated scar-related VT arising from the basal interventricular septum adjacent to the left bundle branch. The tachycardia was characterized by fragmented potentials and slow conduction channels and was entrainable with a short postpacing return cycle, supporting a reentrant mechanism. Targeted ablation rendered VT noninducible. No recurrent arrhythmic events occurred during follow-up. DISCUSSION: VT may present with a narrow QRS morphology in pacemaker-dependent patients when reentrant circuits are located near the His-Purkinje system. TAKE-HOME MESSAGE: Recognition of this uncommon mechanism and advanced electrophysiological mapping are essential for accurate diagnosis and targeted ablation.
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López-Pena et al. (2026) conducted a case report in Ventricular tachycardia with a narrow QRS complex (n=1). Targeted ablation was evaluated on Recurrent arrhythmic events. Targeted ablation of scar-related ventricular tachycardia in a pacemaker-dependent patient rendered the arrhythmia noninducible, with 0 recurrent arrhythmic events during follow-up.
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