Key result
Half-normal saline irrigated RF ablation following bilateral mapping completely eliminates dual-morphology crux PVCs.
Why the study?
Premature ventricular complexes originating from the cardiac crux frequently feature intramural or epicardial substrates, complicating their localization and ablation.
Case Report (n=1)
Bilateral endocardial mapping and lesion enhancement with half-normal saline irrigation can successfully eliminate idiopathic crux PVCs with dual morphologies, potentially obviating the need for epicardial access.
Variable PVC QRS morphologies may signal higher arrhythmia risk; leaves open prospective validation of diagnostic utility.
BACKGROUND: Premature ventricular complexes (PVCs) from the cardiac crux often have intramural or epicardial substrates, complicating localization and ablation. CASE SUMMARY: and/or precordial differences, suggesting a single crux focus with preferential exits. Proximal coronary sinus mapping did not reveal early activation. Stepwise bilateral endocardial mapping identified the earliest basal inferoseptal activation. Standard irrigated radiofrequency catheter ablation caused only transient suppression. Half-normal saline irrigation at the earliest sites and a discrete prepotential achieved complete PVC elimination. DISCUSSION: This case highlights idiopathic crux PVCs with variable morphologies from an intramural focus with preferential exits. A bilateral endocardial lesion-enhancement strategy may obviate epicardial access. TAKE-HOME MESSAGES: Dual morphologies may share 1 crux focus, and bilateral endocardial mapping and lesion enhancement may be required for successful ablation.
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Vo et al. (2026) conducted a case report in Premature ventricular complexes (n=1). Bilateral endocardial mapping and half-normal saline irrigated radiofrequency catheter ablation was evaluated on Complete PVC elimination. Half-normal saline irrigated radiofrequency catheter ablation following bilateral endocardial mapping achieved complete elimination of crux premature ventricular complexes with dual morphologies.
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