Key result
RVOT catheter ablation successfully eliminates PVCs mimicking a left ventricular summit origin.
Why the study?
Catheter ablation of premature ventricular complexes remains challenging in select scenarios, particularly those arising from the LV summit or epicardial sites.
Case Report (n=1)
Intraventricular conduction abnormalities can alter PVC morphology to falsely mimic a left ventricular summit origin, reinforcing the need for comprehensive endocardial mapping before epicardial ablation.
Answers are grounded in this paper and cite their sources.
Thorough endocardial mapping is essential before epicardial ablation in atypical PVCs; hypothesis-generating for conduction abnormalities mimicking LV summit origins.
BACKGROUND: Catheter ablation of premature ventricular complexes (PVCs) remains challenging in select scenarios, particularly those arising from the left ventricular (LV) summit or from epicardial sites. CASE SUMMARY: We report a case of PVCs with a surface electrocardiographic pattern suggestive of LV summit origin but ultimately mapped and successfully ablated in the right ventricular outflow tract (pseudo-LV summit PVC) due to the presence of subtle conduction abnormalities. DISCUSSION: Intraventricular conduction abnormalities may have modified ventricular activation patterns, resulting in a pseudo-LV summit morphology. This case highlights the importance of a systematic mapping approach and cautious interpretation of surface ECG criteria, underscoring the need for comprehensive endocardial evaluation before pursuing epicardial ablation. TAKE-HOME MESSAGES: Intraventricular conduction abnormalities may alter PVC morphology and mislead ECG-based localization. A systematic, stepwise mapping approach-from endocardial to epicardial evaluation-remains essential for accurate diagnosis and effective ablation.
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Nhu et al. (2026) conducted a case report in Premature ventricular complexes (PVC) (n=1). Catheter ablation in the right ventricular outflow tract was evaluated on Elimination of premature ventricular complexes. Catheter ablation in the right ventricular outflow tract successfully eliminated premature ventricular complexes that mimicked a left ventricular summit origin due to subtle intraventricular conduction abnormalities.
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