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February 26, 2020European Journal of Preventive CardiologyOpen Access

Coronary heart disease incidence still decreased between 2006 and 2014 in France, except in young age groups: Results from the French MONICA registries

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Why the study?

Despite observed decreases in coronary heart disease morbidity and mortality rates across the western world, whether acute coronary event rates decreased between 2006 and 2014 in French adults with sex- and age-specific differences was unknown.

Population

Men and women aged 35–74 in three French MONICA population-based registries

Comparison

Acute coronary event trends across sex and age groups over time

Design

Population-based registry study

Authors

AMAline MeirhaegheMMMichèle MontayeKBKatia Biasch

Discussion

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Overview

Declines in CHD incidence were limited to older adults; leaves open whether younger populations require intensified prevention efforts.

Key Points

  • To determine whether acute coronary event attack, incidence, and mortality rates declined between 2006 and 2014 in French adults and assess sex- and age-specific patterns.
  • Analyzed data from three French MONICA population-based registries covering the Lille urban area, Bas-Rhin county, and Haute Garonne county.
  • Monitored all acute coronary events occurring between 2006 and 2014 in men and women aged 35 to 74 years.
  • Age-standardised attack rates decreased annually by 1.5% in men (P = 0.0006) and 2.1% in women (P = 0.002), while incidence rates dropped by 0.9% per year in men (P = 0.03) and 1.8% per year in women (P = 0.002), driven primarily by reductions in adults aged 65–74.
  • Age-standardised mortality rates fell by 3.5% per year in men (P = 0.0004) and 4.3% per year in women (P = 0.0009), while case fatality decreased annually by 1.7% in men (P < 0.0001) and 1.9% in women (P = 0.009).

Structured PICO

P
Population
Men and women aged 35–74 from the French MONICA population-based registries (Lille urban area, Bas-Rhin county, and Haute Garonne county)
O
Outcome
Acute coronary event rates (attack rates, incidence rates, mortality rates, and case fatality)hard clinical

Coronary heart disease incidence and mortality rates decreased in France between 2006 and 2014, but this decline was primarily driven by older adults (65-74 years), highlighting a need for strengthened prevention in younger adults.

Cite This Study

Meirhaeghe et al. (2020) studied this question.

synapsesocial.com/papers/6a1012085725bbd5cc6077a7https://doi.org/10.1177/2047487319899193
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Gender- and age-specific trends in coronary heart disease mortality in France from 2000 to 2007: results from the MONICA registers2012 · 26 citations
  2. 2Coronary heart disease trends in France and elsewhere2000
  3. 3Trends and geographical disparities in coronary heart disease in France: are results concordant when different definitions of events are used?1999 · 27 citations
  4. 4Incidence, recurrence, and case fatality rates for myocardial infarction in southwestern France, 1985 to 19932000 · 47 citations
  5. 5Comparison of the rates of stroke and acute coronary events in northern France2018 · 5 citations