Why the study?
Does antihypertensive drug therapy account for the observed decreases in systolic blood pressure trends in US adults between 1960 and 1980?
Population
US adults aged 35-74 years from three successive US health examination surveys (1960-1980)
Comparison
Antihypertensive drug therapy vs No antihypertensive drug therapy
Design
Cross-sectional
Follow-up
1960 to 1980
Authors
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May inform attribution of historical BP trends without changing practice; leaves open independent primary prevention effects in younger adults pending longitudinal data.
Does antihypertensive drug therapy account for the observed decreases in systolic blood pressure trends in US adults between 1960 and 1980?
Decreases in systolic blood pressure between 1960 and 1980 in US adults over 44 were largely driven by antihypertensive medication, while younger adults showed improvements likely due to primary prevention.
Kumanyika et al. (1998) studied this question.
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