January 12, 2021American Journal of Preventive CardiologyOpen Access

Physical activity and sedentary behaviour in secondary prevention of coronary artery disease: A review

Q: What is the clinical evidence from this study?

Study design: Systematic Review. Population: Coronary artery disease (CAD) (n=33579). Intervention: Exercise training and physical activity vs. Usual care or physical inactivity. Primary outcome: Physical fitness, quality of life, rehospitalizations, and mortality.

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Key result

Exercise and high physical activity improve fitness and cut rehospitalizations and mortality in established CAD.

n=33,579

Why the study?

Physical exercise is part of CAD management, but CAD patients generally have low physical activity and high sedentary behaviour.

Does exercise training and increased physical activity improve clinical outcomes and quality of life in patients with coronary artery disease?

Study Design

Type

Systematic Review (n=33,579)

Structured PICO

Does exercise training and increased physical activity improve clinical outcomes and quality of life in patients with coronary artery disease?

Population

Patients with stable coronary artery disease (CAD), recent acute coronary syndrome (ACS), or recent revascularization (PCI or CABG) (25 studies, n=33,579).

Intervention

Exercise training, physical activity interventions, and habitual physical activity.

Comparator

Usual care, low physical activity, or high sedentary behavior.

Outcome

Physical fitness (maximal oxygen consumption), quality of life (QoL), rehospitalizations, and mortality.

This systematic review confirms that exercise training and increased physical activity improve physical fitness, quality of life, and survival in patients with coronary artery disease, highlighting the importance of lifestyle interventions in secondary prevention.

Limitations

Results indicating positive influence of exercise training are mostly based on limited follow-up of 12 months or less.
Patients often do not continue training after the intervention period, causing beneficial effects to disappear.
Supervised exercise interventions require significant financial resources and professional staff.
Positive effects of exercise are mostly based on limited follow-up (12 months or less)
Patients often do not continue training after the exercise intervention period, causing beneficial effects to disappear

Discussion

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Implication

Supports routine exercise in CAD secondary prevention; confirms benefits on fitness, QoL, and survival.

Cite This Study

Vasankari et al. (2021) conducted a systematic review in Coronary artery disease (CAD) (n=33,579). Exercise training and physical activity vs. Usual care or physical inactivity was evaluated on Physical fitness, quality of life, rehospitalizations, and mortality. Exercise training and high physical activity improve maximal oxygen consumption and quality of life, and reduce rehospitalizations and mortality among patients with established coronary artery disease.

synapsesocial.com/papers/6a1018f8d13714ec96ff2846 https://doi.org/10.1016/j.ajpc.2021.100146

Topics

Coronary artery disease

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Physical activity and sedentary behaviour in secondary prevention of coronary artery disease: A review

Study Design

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Topics

Physical activity and sedentary behaviour in secondary prevention of coronary artery disease: A review

Study Design

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider