What question did this study set out to answer?

To evaluate the impact of pharmacist-initiated home blood pressure monitoring and physician recommendations on blood pressure control, medication compliance, and quality of life.

November 1, 2000Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy

Effect of Pharmacist Intervention and Initiation of Home Blood Pressure Monitoring in Patients with Uncontrolled Hypertension

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Why the study?

Does pharmacist intervention combined with home blood pressure monitoring improve blood pressure control in patients with uncontrolled hypertension?

Population

36 patients with uncontrolled stage 1 or 2 hypertension.

Comparison

Pharmacist-initiated home blood pressure… vs No home monitors or pharmacist intervention.

Design

RCT, Randomized

Follow-up

6 months

Authors

BMBrenda MehosUniversity of Colorado Hospital JSJoseph J. SaseenPreventive Cardiology EMEric J. MacLaughlinPreventive Cardiology

Discussion

Member takes

Implication

Pharmacist intervention with home BP monitoring improves control in uncontrolled hypertension; extends evidence for collaborative care models.

Key Points

To evaluate the impact of pharmacist-initiated home blood pressure monitoring and physician recommendations on blood pressure control, medication compliance, and quality of life.
Prospective randomized controlled study of 36 patients with uncontrolled stage 1 or 2 hypertension followed for 6 months.
Intervention subjects (n=18) received home monitors and diaries with telephone review by a clinical pharmacist, who advised physicians on therapy changes if monthly means were ≥140/90 mm Hg, while control subjects (n=18) received usual care.
Intervention subjects achieved significant mean reductions in systolic (17.0 mm Hg, p < 0.0001) and diastolic pressure (10.5 mm Hg, p < 0.0001), whereas control reductions were not statistically significant (7.0 mm Hg, p = 0.12; 3.8 mm Hg, p = 0.09).
Medication regimen modifications occurred in 83.3% (15/18) of intervention patients compared with 33.0% (6/18) of control patients (p < 0.01), with 8 intervention versus 4 control subjects reaching blood pressures below 140/90 mm Hg at 6 months.
Therapy compliance and SF-36 quality of life scores were not significantly altered between groups.

Structured PICO

Does pharmacist intervention combined with home blood pressure monitoring improve blood pressure control in patients with uncontrolled hypertension?

Population

36 patients with uncontrolled stage 1 or 2 hypertension.

Intervention

Pharmacist-initiated home blood pressure monitoring (provided with monitors, a diary, and instructions to measure blood pressure twice every morning), telephone evaluation by a clinical pharmacist, and recommendations to the family physician if mean monthly values were ≥140/90 mm Hg.

Comparator

No home monitors or pharmacist intervention.

Outcome

Blood pressure control (mean absolute reductions in systolic and diastolic pressures) at 6 months.surrogate

Pharmacist-initiated home blood pressure monitoring and intervention significantly improves blood pressure control in patients with uncontrolled hypertension, likely driven by increased modifications to drug therapy.

Cite This Study

Mehos et al. (2000) studied this question.

synapsesocial.com/papers/6a101d7e8090e499da60a650 https://doi.org/10.1592/phco.20.17.1384.34891

Topics

Hypertension management

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Implication

Pharmacist intervention with home BP monitoring improves control in uncontrolled hypertension; extends evidence for collaborative care models.

Effect of Pharmacist Intervention and Initiation of Home Blood Pressure Monitoring in Patients with Uncontrolled Hypertension

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Effect of Pharmacist Intervention and Initiation of Home Blood Pressure Monitoring in Patients with Uncontrolled Hypertension

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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