Should all patients with atrial fibrillation receive warfarin? Evidence from randomized clinical trials
Why the study?
Should all patients with atrial fibrillation receive warfarin for stroke prevention?
Population
Patients with atrial fibrillation
Design
Review
Authors
Discussion
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Member takes
Implication
May support broader anticoagulant use in AF with lower INR targets; leaves open confirmation by randomized trials.
Structured PICO
Should all patients with atrial fibrillation receive warfarin for stroke prevention?
P
Population
Patients with atrial fibrillation
I
Intervention
Anticoagulants (warfarin) and aspirin
This review highlights the need for wider use of anticoagulants in atrial fibrillation while emphasizing the importance of identifying minimum effective doses to balance stroke prevention and bleeding risks.
Cite This Study
Cleland et al. (1996) studied this question.