Why the study?
Does an endogenous circadian rhythmicity, independent from sleep/wake cycles, exist in autonomic nervous system function?
Does an endogenous circadian rhythmicity, independent from sleep/wake cycles, exist in autonomic nervous system function?
The study demonstrates that the circadian pacemaker controls both sympathetic and vagal limbs of the autonomic nervous system independently of sleep/wake cycles, which may contribute to cardiovascular mortality patterns.
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Endogenous circadian autonomic control may underlie morning CV risk; leaves open causal contribution to clinical events.
Hilton et al. (2002) studied this question.
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