What question did this study set out to answer?

To determine the independent contributions of the sleep and circadian systems to variations in cardiac autonomic nervous system activity.

October 1, 1997AJP Heart and Circulatory Physiology

Sleep and circadian influences on cardiac autonomic nervous system activity

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Why the study?

Does sleep versus sleep deprivation affect the circadian rhythm of cardiac autonomic nervous system activity in supine subjects?

Population

12 supine subjects

Comparison

26-h constant routine allowing sleep during… vs 26-h constant routine not permitting sleep

Design

Other, counterbalanced

Follow-up

Two 26-h routines separated by 1 week

Authors

HBHelen J. BurgessUniversity of Michigan JTJohn TrinderSouth Eastern Health and Social Care Trust YKYoung Jin KimElectrophysiology

Discussion

Member takes

Implication

Supports distinct circadian versus sleep regulation of cardiac parasympathetic and sympathetic activity; hypothesis-generating for autonomic monitoring in sleep disorders.

Key Points

To determine the independent contributions of the sleep and circadian systems to variations in cardiac autonomic nervous system activity.
Twelve supine participants completed two counterbalanced 26-hour constant-routine protocols separated by one week: one involving continuous wakefulness and the other permitting sleep during the habitual sleep phase.
Parasympathetic nervous system activity was quantified via respiratory sinus arrhythmia using spectral analysis of cardiac beat-to-beat intervals.
Sympathetic nervous system activity was measured primarily by preejection period estimated with impedance cardiography, alongside electrocardiogram T-wave amplitude and 0.1-Hz spectral peaks.
Respiratory sinus arrhythmia displayed an endogenous 24-hour rhythm that persisted independently of whether sleep occurred, demonstrating circadian control of parasympathetic activity.
Preejection period showed a 24-hour rhythm only when sleep was permitted, indicating that sympathetic nervous system activity is primarily governed by the sleep system.

Structured PICO

Does sleep versus sleep deprivation affect the circadian rhythm of cardiac autonomic nervous system activity in supine subjects?

Population

12 supine subjects

Intervention

26-h constant routine allowing sleep during normal sleep phase

Comparator

26-h constant routine not permitting sleep

Outcome

Changes in cardiac autonomic nervous system (ANS) activity, including parasympathetic activity (respiratory sinus arrhythmia) and sympathetic activity (preejection period, 0.1-Hz peak, T wave amplitude, and heart rate)surrogate

Parasympathetic nervous system activity is primarily driven by the circadian system, whereas sympathetic nervous system activity is primarily driven by the sleep system.

Cite This Study

Burgess et al. (1997) studied this question.

synapsesocial.com/papers/6a101e76d8c5cf602efdb3c8 https://doi.org/10.1152/ajpheart.1997.273.4.h1761

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Implication

Supports distinct circadian versus sleep regulation of cardiac parasympathetic and sympathetic activity; hypothesis-generating for autonomic monitoring in sleep disorders.

Sleep and circadian influences on cardiac autonomic nervous system activity

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Sleep and circadian influences on cardiac autonomic nervous system activity

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider