Why the study?
Does endogenous insulin release differentially affect lipolysis after adrenergic stimulation in obese subjects with versus without type 2 diabetes?
Population
28 obese females (14 with type 2 diabetes and 14 non-diabetic controls)
Comparison
Intravenous glucose load following 60 minutes of… vs Obese non-diabetic controls
Design
Other
Authors
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Impaired antilipolysis in T2D may worsen lipid dysregulation; leaves open whether this mechanism warrants targeted interventions.
Does endogenous insulin release differentially affect lipolysis after adrenergic stimulation in obese subjects with versus without type 2 diabetes?
Obese subjects with type 2 diabetes exhibit an impaired insulin-induced inhibition of lipolysis following norepinephrine stimulation compared to healthy obese controls.
Schümann et al. (2017) studied this question.
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