Why the study?
Existing arterial simulators have limited capacity to explore diverse vessel wall tensional states to study pulse wave velocity dependency.
Population
Arterial surrogate in a novel arterial simulator
Comparison
Independent adjustment of inner and outer pressures up to three times atmospheric pressure
Design
Experimental in vitro validation study
Authors
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Provides controlled in vitro model for pressure-PWV relations; leaves open human validation before clinical use.
A novel arterial simulator successfully demonstrated that increasing transmural pressure leads to an increase in pulse wave velocity, providing an in vitro model for studying arterial stiffness.
Filippi et al. (2023) studied this question.
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